HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanol → HCID 178478705, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | Water | HCID 962 | — |
| Reactant | HCID 45357346 | HCID 45357346 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | HCID 178478705 | HCID 178478705 | — |
Reaction Steps
A solution of 1.0 g. of 2-amino-1-[5-amino-1-(phenylmethyl)-1H-imidazol-4-yl]ethanone dihydrochloride in 100 ml. of 70:20:10 methanol:water:acetic acid is hydrogenated over 0.52 g. of 20% palladium-on-carbon at 50 p.s.i. until hydrogen uptake ceases. The catalyst is removed by filtration and the filtrate is evaporated at reduced pressure to give 2-amino-1-(5-amino-1H-imidazol-4-yl)ethanone dihydrochloride; m.p. above 250° dec.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04117229 |
| Source dataset | uspto-grants-1978_09 |
| ORD ID | ord-707a4ff2625348feb1ccf816c8d30369 |
| Source note | uspto-grants-1978_09 |