2-Hexanol → 2-Hexyl methanesulfonate

HRID 1764850Notes

Reaction equation

[CH3:1][CH:2]([OH:7])[CH2:3][CH2:4][CH2:5][CH3:6].[CH3:8][S:9](Cl)(=[O:11])=[O:10]>>[CH3:8][S:9]([O:7][CH:2]([CH2:3][CH2:4][CH2:5][CH3:6])[CH3:1])(=[O:11])=[O:10]

Participants

Reactant 2

HCID 122972-Hexanol

HCID 31297Methanesulfonyl chloride

Product 1

HCID 153694402-Hexyl methanesulfonate

Procedure

The title compound was prepared by following the general procedure of Example 43 for mesylation as a colorless oil (408 mg, 68%) from 2-hexanol (312 mg, 2.90 mmol) and methanesulfonyl chloride (500 mg, 4.40 mmol). 1H NMR (CDCl3, 300 MHz) δ0.89-0.94 (m, 3H), 1.31-1.43 (m, 5H), 1.57-1.71 (m, 4H), 2.99 (s, 3H), 4.76-4.82 (m, 1H) ppm.

Sources & evidence

ORD record: ord-b69d3f4729cc41a5ad877e14fab5f86a
Source dataset: uspto-grants-2007_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: USRE039679E1

Reaction notes

Loading…