HCID 23115712, compound → 1-(3-Hydroxy-1-hexyl)-2,3,4-trifluorobenzene

HRID 1765000Notes

Reaction equation

HRID 1765000 reaction equation
[OH:1][CH:2]([CH2:14][CH2:15][CH3:16])[C:3]#[C:4][C:5]1[CH:10]=[CH:9][C:8]([F:11])=[C:7]([F:12])[C:6]=1[F:13].[H][H]>C(O)C.[C].[Pd]>[OH:1][CH:2]([CH2:14][CH2:15][CH3:16])[CH2:3][CH2:4][C:5]1[CH:10]=[CH:9][C:8]([F:11])=[C:7]([F:12])[C:6]=1[F:13]

Participants

5

Reactant 2

HCID 23115712HCID 23115712, compoundHCID 178418361HCID 178418361, compound

Product 1

HCID 231157091-(3-Hydroxy-1-hexyl)-2,3,4-trifluorobenzene

Reagents, catalysts & solvents 2

HCID 178418390HCID 178418390, compoundCatalystHCID 702EthanolSolvent

Procedure

After 1-(3-hydroxy-1-hexynyl)-2,3,4-trifluorobenzene was dissolved in ethanol, 5% palladium carbon (50% in water) was added thereto, and stirred for 6 hours at a hydrogen pressure of 0.5 MPa, and the mixture was left to stand overnight. After palladium carbon was removed by filtration, the solvent was evaporated under a reduced pressure to obtain 1-(3-hydroxy-1-hexyl)-2,3,4-trifluorobenzene.

Workup

  1. waitthe mixture was left
  2. customAfter palladium carbon was removed by filtration
  3. customthe solvent was evaporated under a reduced pressure

Sources & evidence

ORD record
ord-df9f7b75b88247ce807619c06e8e164f
Source dataset
uspto-grants-2007_06
Patent number
US07226644B2

Reaction notes

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