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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1765131Generated: November 1, 2026

3-Methoxyaniline → HCID 22732501, compound

https://huagongshe.com/reaction/1765131

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-MethoxyanilineHCID 10824—
Reactant4-CHLORO-5-METHOXY-2-(2-PYRIDINYL)PYRIMIDINEHCID 2763500—
ProductHCID 22732501HCID 22732501—

Reaction Steps

The title compound was prepared from 4-chloro-5-methoxy-2-(2-pyridinyl)pyrimidine (100 mg, 0.451 mmol) and m-anisidine (51 μl, 0.451 mmol) similar to Example 13 and isolated as a tan oily liquid (63 mg, 45%). 1H NMR (CDCl3): 8.76–8.74 (m, 1H), 8.37 (dd, J=1.1, 8.0 Hz, 1H), 8.05 (s, 1H), 7.79–7.73 (m, 2H), 6.65–6.62 (m, 1H), 3.92 (s, 3H), 3.84 (s, 3H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07226927B2
Source datasetuspto-grants-2007_06
ORD IDord-dd36bde307be4117b26d9ef55cf99458
Source noteuspto-grants-2007_06