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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1765148Generated: October 31, 2026

3-Isopropylaniline → HCID 9814966, compound

https://huagongshe.com/reaction/1765148

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-IsopropylanilineHCID 458679—
Reactant4-Chloro-6-methyl-2-(pyridin-2-yl)pyrimidineHCID 2763395—
ProductHCID 9814966HCID 9814966—

Reaction Steps

The title compound was prepared from a mixture of 4-chloro-6-methyl-2-(2-pyridinyl)pyrimidine (50 mg, 0.243 mmol) and 3-isopropylaniline (33 μl, 0.243 mmol) similar to Example 13 and isolated as a gray oil (70 mg, 95%). 1H NMR (CDCl3): 8.79–8.77 (m, 1H), 8.47–8.43 (m, 1H), 7.81–7.75 (m, 1H), 7.35–7.25 (m, 3H), 7.17–7.12 (m, 2H), 7.02 (d, J=7.5 Hz, 1H), 2.93–2.84 (m, 1H), 2.45 (s, 3H), 1.24 (d, J=6.9 Hz, 6H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07226927B2
Source datasetuspto-grants-2007_06
ORD IDord-b92dcb2590ed4ee388103e18b8f23d17
Source noteuspto-grants-2007_06