Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1765151Generated: October 30, 2026

3-Methoxyphenol → HCID 22732505, compound

https://huagongshe.com/reaction/1765151

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-MethoxyphenolHCID 9007—
Reactant4-Chloro-6-methyl-2-(pyridin-2-yl)pyrimidineHCID 2763395—
ProductHCID 22732505HCID 22732505—

Reaction Steps

The title compound was prepared from a mixture of 4-chloro-6-methyl-2-(2-pyridinyl)pyrimidine (50 mg, 0.243 mmol) and 3-methoxyphenol (27 μl, 0.243 mmol) similar to Example 13 and isolated as a white oil (24 mg, 34%). 1H NMR (CDCl3): 8.79–8.76 (m, 1H), 8.26–8.23 (m, 1H), 7.75–7.69 (m, 1H), 7.33–7.28 (m, 2H), 6.82–6.72 (m, 3H), 6.58 (s, 1H), 3.77 (s, 3H), 2.58 (s, 3H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07226927B2
Source datasetuspto-grants-2007_06
ORD IDord-c67d0478856d4b349ef570d51f09575f
Source noteuspto-grants-2007_06