3,5-Dimethoxyaniline → HCID 22732475, compound

Participants

Reaction Steps

The title compound was prepared from a mixture of 4-chloro-2-(3-pyridinyl)-6-(trifluoromethyl)pyrimidine (50 mg, 0.193 mmol) and 3,5-dimethoxyaniline (44 mg, 0.290 mmol) similar to Example 117 and isolated as a yellow solid (29 mg, 38%). 1H NMR (DMSO-d6): 10.32 (s, 1H), 9.48–9.46 (m, 1H), 8.76–8.74 (m, 1H), 8.62–8.58 (m, 1H), 7.63–7.58 (m, 1H), 7.14 (s, 1H), 7.06 (s, 2H), 6.32 (s, 1H), 3.80 (s, 6H).

Provenance & Evidence