HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanone, 1-(2-amino-4,5-dimethoxyphenyl)- → HCID 22732513, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanone, 1-(2-amino-4,5-dimethoxyphenyl)- | HCID 602085 | — |
| Reactant | 4-Chloro-2-(pyridin-3-yl)-6-(trifluoromethyl)pyrimidine | HCID 1485990 | — |
| Product | HCID 22732513 | HCID 22732513 | — |
Reaction Steps
The title compound was prepared from a mixture of 4-chloro-2-(3-pyridinyl)-6-(trifluoromethyl)pyrimidine (50 mg, 0.193 mmol) and 2-amino-4,5-dimethoxyacetophenone (56 mg, 0.290 mmol) similar to Example 117 and isolated as a tan solid (24 mg, 30%). 1H NMR (CDCl3): 12.49 (s, 1H), 9.65–9.64 (m, 1H), 8.86 (s, 1H), 8.74–8.70 (m, 2H), 7.45–7.41 (m, 1H), 7.35 (s, 1H), 6.99 (s, 1H), 4.12 (s, 3H), 3.95 (s, 3H), 2.68 (s, 3H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07226927B2 |
| Source dataset | uspto-grants-2007_06 |
| ORD ID | ord-cea8ece323b049b38a31f9c1a846e0ff |
| Source note | uspto-grants-2007_06 |