4-Chloro-2,5-dimethoxyaniline → HCID 22732435, compound

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The title compound was prepared from a mixture of 4-chloro-2-(2-pyridinyl)-6-(trifluoromethyl)pyrimidine (50 mg, 0.193 mmol) and 4-chloro-2,5-dimethoxyaniline (54 mg, 0.290 mmol) similar to Example 117 and isolated as a brown solid (58 mg, 73%). 1H NMR (CDCl3): 8.84–8.82 (m, 1H), 8.61–8.57 (m, 1H), 7.93–7.87 (m, 1H), 8.50 (bs, 1H), 7.66 (s, 1H), 7.49–7.45 (m, 1H), 7.02 (s, 1H), 7.01 (s, 1H), 4.07 (s, 3H), 3.92 (s, 3H).

Provenance & Evidence