HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 211811, compound → HCID 69456393, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 211811 | HCID 211811 | — |
| Reactant | 4-Chloro-2-(pyridin-3-yl)-6-(trifluoromethyl)pyrimidine | HCID 1485990 | — |
| Product | HCID 69456393 | HCID 69456393 | — |
Reaction Steps
The title compound was prepared from 4-chloro-2-(3-pyridinyl)-6-trifluoromethylpyrimidine (40 mg, 0.154 mmol) and 2,5-dimethoxyphenylethylamine (28 mg, 0.232 mmol) similar to Example 186 and was isolated as an off white solid (35 mg, 54% yield). 1H NMR (CDCl3): 9.59 (brs, 1H), 8.69 (d, J=4.8 Hz, 1H), 7.37 (dd, J=4.8, 8.4 Hz, 1H), 6.76 (m, 3H), 3.95 (s, 3H), 3.90 (s, 3H), 3.00 (t, 2H), 1.67 (s, 2H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07226927B2 |
| Source dataset | uspto-grants-2007_06 |
| ORD ID | ord-9ecb41da3296402687c2617887f4cec9 |
| Source note | uspto-grants-2007_06 |