HuagongsheHuagongshe Chemistry Print Report · For research reference only
3,4,5-Trichloroaniline → HCID 22732356, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3,4,5-Trichloroaniline | HCID 12469 | — |
| Reactant | 4-Chloro-2-(pyridin-3-yl)-6-(trifluoromethyl)pyrimidine | HCID 1485990 | — |
| Product | HCID 22732356 | HCID 22732356 | — |
Reaction Steps
The title compound was prepared from 4-chloro-2-(3-pyridinyl)-6-trifluoromethylpyrimidine (50 mg, 0.192 mmol) and 3,4,5-trichloroaniline (56 mg, 0.288 mmol) similar to Example 180 and was isolated as a white solid (30 mg, 37%). 1H NMR (CDCl3): 9.58 (d, J=1.5 Hz, 1H), 8.99 (ddd, J=8.4, 4.9, 1.5 Hz, 1H), 8.79 (dd, J=5.4, 1.5 Hz, 1H), 7.99 (s, 1H), 7.76 (dd, J=7.8, 5.1 Hz, 1H), 7.40 (s, 1H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07226927B2 |
| Source dataset | uspto-grants-2007_06 |
| ORD ID | ord-375aa3a13c094e118667876e2066c48f |
| Source note | uspto-grants-2007_06 |