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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1765298Generated: November 2, 2026

4-Chloro-2-(pyridin-3-yl)-6-(trifluoromethyl)pyrimidine → HCID 22732496, compound

https://huagongshe.com/reaction/1765298

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Chloro-2-(pyridin-3-yl)-6-(trifluoromethyl)pyrimidineHCID 1485990—
ReactantHCID 22732407HCID 22732407—
ProductHCID 22732496HCID 22732496—

Reaction Steps

The title compound was prepared from 4-chloro-2-(3-pyridinyl)-6-trifluoromethylpyrimidine (50 mg, 0.192 mmol) and 4-amino-3-methoxydibenzofuran (61 mg, 0.288 mmol) similar to Example 185 and was isolated as a solid (6 mg, 7%). 1H NMR (CDCl3): 9.73 (brs, 1H), 8.88 (d, J=7.8 Hz, 1H), 8.77 (brs, 1H), 7.89 (m, 1H), 7.19–7.59 (m, 6H), 7.02 (s, 1H), 4.05 (s, 3H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07226927B2
Source datasetuspto-grants-2007_06
ORD IDord-1e30cf9c36ed4cd7b5cb121655a6575f
Source noteuspto-grants-2007_06