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HRID1765710

反应详情

EQUATION

反应方程式

HRID 1765710 的结构方程式

REACTANTS

反应物

2
结构：CCOC=O
HCID8025

Ethyl formate

C3H6O2

结构：CC1(C)CC(C)(C)c2cc(Br)cc(CNC3CC3)c2O1
HCID21107218

未命名化合物

2 次

PRODUCTS

生成物

1
结构：CC1(C)CC(C)(C)c2cc(Br)cc(CN(C=O)C3CC3)c2O1
HCID21107219

未命名化合物

收率 100%

PROCEDURE

实验过程

A solution of 6-bromo-8-[(cyclopropyl-amino)-methyl]-2,2,4,4-tetramethyl-chroman (Intermediate 7, 1.4 g, 4.14 mmol) in ethyl formate was refluxed for 6 h. The solvent was distilled off in vacuo to afford the title compound as a clear oil (1.56 g, 100%).

WORKUP

后处理

  1. distillationThe solvent was distilled off in vacuo