Potassium Carbonate → HCID 86600201, compound

HRID 1765902Notes

Reaction equation

HRID 1765902 reaction equation
[CH2:1]([O:3][C:4]([C:6]1[C:15]2[C:10](=[CH:11][C:12]([C:16]#[C:17][Si](C)(C)C)=[CH:13][CH:14]=2)[C:9]([CH3:23])([CH3:22])[CH2:8][C:7]=1[CH3:24])=[O:5])[CH3:2].C(=O)([O-])[O-].[K+].[K+]>C(O)C>[CH2:1]([O:3][C:4]([C:6]1[C:15]2[C:10](=[CH:11][C:12]([C:16]#[CH:17])=[CH:13][CH:14]=2)[C:9]([CH3:23])([CH3:22])[CH2:8][C:7]=1[CH3:24])=[O:5])[CH3:2]

Participants

4

Reactant 2

HCID 11430Potassium CarbonateHCID 58883474HCID 58883474, compound2×

Product 1

HCID 86600201HCID 86600201, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Following general procedure F and using 2,4,4-trimethyl-6-trimethylsilanylethynyl-3,4-dihydro-naphthalene-1-carboxylic acid ethyl ester (Intermediate 199, 0.31 g, 0.92 mmol), ethanol (2 mL) and potassium carbonate (0.3 g, 2.2 mmol), the title compound was obtained (0.26 g, >100%).

Sources & evidence

ORD record
ord-5849ffe6c3e64562a7c8aeec791e0c39
Source dataset
uspto-grants-2007_06
Patent number
US07226951B2

Reaction notes

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