Ethanol → HCID 21109100, compound

Participants

Reaction Conditions

Reaction Steps

DIPEA (20.0 ml) was added to a stirred solution of ethyl 5-cyano-4(3-nitrophenyl)-2-phenyl-6-(ethoxycarbonylmethylthio)-pyrimidine (example 31(c), 19.7 g) in a mixture of abs. EtOH (100 ml) and toluene p.a. (100 ml). After 48 h at 100° C., the mixture was cooled to 0° C. The resulting precipitate was filtered off, washed with cold EtOH and dried in vacuo at 40° C.

Provenance & Evidence