huagongshe.com
HRID1766179

反应详情

EQUATION

反应方程式

HRID 1766179 的结构方程式

REACTANTS

反应物

3
结构：O=C(O)CCC(=O)c1ccc(Cl)c(Cl)c1
HCID289763

4-(3,4-dichlorophenyl)-4-oxobutanoic acid

C10H8Cl2O3

结构：CN(C)C(On1nnc2ccccc21)=[N+](C)C.F[B-](F)(F)F
HCID2733207

O-(Benzotriazol-1-yl)-N,N,N′,N′-tetramethyluronium tetrafluoroborate

C11H16BF4N5O

结构：O=C1Nc2ccccc2CN1C1CCNCC1
HCID11042597

3-(Piperidin-4-yl)-3,4-dihydroquinazolin-2(1H)-one

C13H17N3O

PRODUCTS

生成物

1
结构：O=C(CCC(=O)N1CCC(N2Cc3ccccc3NC2=O)CC1)c1ccc(Cl)c(Cl)c1
HCID21109908

未命名化合物

收率 73%

PROCEDURE

实验过程

Prepared analogously to Example 2 from 3,4-dichloro-γ-oxobenzenebutanoic acid and 3-(4-piperidinyl)-3,4-dihydro-2(1H)-quinazolinone in the presence of TBTU in a yield of 73% of theoretical. Colourless crystals, m.p. 224–226° C. and Rf 0.15 (El EE).