反应详情

A solution of 20.0 g (0.5355 mol) of 1-(diphenylmethyl)-3-[(2-nitrophenylmethyl)amino]-azetidine in 200 ml of methanol was hydrogenated in the presence of 4 g of 5% rhodium/charcoal for 5 hours at ambient temperature. The catalyst was filtered off, the filtrate was concentrated by evaporation in vacuo. 17.7 g (96% of theoretical) of a colourless, highly viscous oil were obtained, which was further processed without any additional purification.

1. filtrationThe catalyst was filtered off
2. concentrationthe filtrate was concentrated by evaporation in vacuo
3. custom17.7 g (96% of theoretical) of a colourless, highly viscous oil were obtained
4. customwhich was further processed without any additional purification