HRID1766189

反应详情

EQUATION

反应方程式

HRID 1766189 的结构方程式

AUXILIARIES

试剂、催化剂与溶剂

1

PROCEDURE

实验过程

A mixture of 75 g (0.235 mol) of 1-(diphenylmethyl)-3-(methanesulphonyloxy)-azetidine, 47.1 g (0.254 mol) of potassium phthalimide and 800 ml of dimethylformamide was refluxed for 1½ hours, during which time a fine precipitate gradually settled out. After cooling the precipitate was filtered off and the solvent was evaporated off in vacuo, finally under a high vacuum. The colourless residue crystallised when left to stand. Yield: 78.0 g (90% of theoretical). Rf=0.95 (El N).

WORKUP

后处理

  1. temperaturewas refluxed for 1½ hours, during which time a fine precipitate
  2. temperatureAfter cooling the precipitate
  3. filtrationwas filtered off
  4. customthe solvent was evaporated off in vacuo, finally under a high vacuum
  5. customThe colourless residue crystallised when
  6. waitleft