Lithium Hydroxide → Lithium 3-oxo-3-{[3-(trifluoromethyl)phenyl]amino}propanoate

Participants

Reaction Steps

To a tetrahydrofuran (350 ml) solution of Example 34A (5 g, 18.17 mmol) is added lithium hydroxide (435 mg, 18.17 mmol) in water (150 ml). The solution is stirred at room temperature for 4 hours, and then concentrated to afford a white solid. The product is used without further purification.

Provenance & Evidence