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HRID1766469

反应详情

EQUATION

反应方程式

HRID 1766469 的结构方程式

REACTANTS

反应物

4
结构：COCCO
HCID8019

2-Methoxyethanol

C3H8O2

结构：OB(O)c1ccc(Cl)cc1
HCID74299

Benzeneboronic acid, p-chloro-

C6H6BClO2

结构：CC(C)(CN)CO
HCID117326

1-Propanol, 3-amino-2,2-dimethyl-

C5H13NO

结构：COC(=O)c1cnc(O)c(Br)c1
HCID178498843

未命名化合物

PRODUCTS

生成物

1
结构：COCCOc1ncc(C(=O)NCC(C)(C)CO)cc1-c1ccc(Cl)cc1
HCID11951834

未命名化合物

PROCEDURE

实验过程

The title compound was synthesized in analogy to Example 102, using 5-bromo-6-hydroxy-nicotinic acid methyl ester, 2-methoxyethanol, (4-chloro-phenyl)-boronic acid and 3-amino-2,2-dimethyl-1-propanol as starting materials to yield 5-(4-chloro-phenyl)-N-(3-hydroxy-2,2-dimethyl-propyl)-6-(2-methoxy-ethoxy)-nicotinamide. MS (ISP) 393.1 (M+H)+.

WORKUP

后处理

  1. customThe title compound was synthesized in analogy to Example 102