Dichloromethane → Hydrochloric Acid

HRID 176648Notes

Reaction equation

HRID 176648 reaction equation
[CH2:37]1[NH:38][CH2:39][CH2:40][O:41][CH2:42]1.[CH3:12][O:13][CH2:14][c:15]1[cH:16][cH:17][c:18](-[c:21]2[c:22]([N:27]3[CH2:28][CH2:29][N:30]([CH2:33][CH2:34][NH:35][CH3:36])[CH2:31][CH2:32]3)[n:23][cH:24][cH:25][n:26]2)[cH:19][cH:20]1.[Cl:43][CH2:44][Cl:45].[F:1][c:2]1[cH:3][cH:4][c:5]([S:8](=[O:9])(=[O:10])[Cl:11])[cH:6][cH:7]1>>[ClH:11].[F:1][c:2]1[cH:3][cH:4][c:5]([S:8](=[O:9])(=[O:10])[N:35]([CH2:34][CH2:33][N:30]2[CH2:29][CH2:28][N:27]([c:22]3[c:21](-[c:18]4[cH:17][cH:16][c:15]([CH2:14][O:13][CH3:12])[cH:20][cH:19]4)[n:26][cH:25][cH:24][n:23]3)[CH2:32][CH2:31]2)[CH3:36])[cH:6][cH:7]1

Participants

6

Reactant 4

HCID 6344DichloromethaneHCID 8083MorpholineHCID 95884-Fluorobenzenesulfonyl chlorideHCID 67367004{2-[3'-(4-Methoxymethyl-phenyl)-2,3,5,6-tetrahydro-[1,2']bipyrazinyl-4-yl]-ethyl}-methyl-amine

Product 2

HCID 313Hydrochloric AcidHCID 592522274-fluoro-N-[2-[4-[3-[4-(methoxymethyl)phenyl]pyrazin-2-yl]piperazin-1-yl]ethyl]-N-methylbenzenesulfonamide

Sources & evidence

ORD record
ord-2a51d7382def413f9695814e4bb5bfd9
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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