HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyclopropanemethanol → HCID 21109689, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyclopropanemethanol | HCID 75644 | — |
| Reactant | 5-Bromo-6-chloropyridine-3-carboxylic acid | HCID 285433 | — |
| Reactant | 4-Fluorophenylboronic acid | HCID 285645 | — |
| Reactant | 912454-49-0 | HCID 21109690 | — |
| Product | HCID 21109689 | HCID 21109689 | — |
Reaction Steps
The title compound was synthesized in analogy to Example 75, using 5-bromo-6-chloro-3-pyridinecarboxylic acid, hydroxymethyl-cyclopropan, 4-fluorophenylboronic acid and 1-amino-2-cyclobutyl-propan-2-ol hydrochloride as starting materials to yield (RS)-N-(2-cyclobutyl-2-hydroxy-propyl)-6-cyclopropylmethoxy-5-(4-fluoro-phenyl)-nicotinamide. MS (ISP) 399.0 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07229999B2 |
| Source dataset | uspto-grants-2007_06 |
| ORD ID | ord-3c73b29630ed4ddb912bcaa737bc1b0c |
| Source note | uspto-grants-2007_06 |