反应详情

1-Chloro-4-dodecyloxythioxanthone was prepared as follows. A solution of 1-chloro-4-hydroxythioxanthone (14.0 g, 0.05 mol), K2CO3 (8.09, 0.06 mol) in acetone (250 mL) was stirred and refluxed for 10 min. Bromododecane (20.0 g, 0.08 mol) was added and the resulting mixture was stirred for 24 h under reflux. The reaction was then cooled to room temperature and quenched with water (500 mL). The obtained solid was filtered, washed with water, purified by recrystalized from isopropanol to give the 1-chloro-4-dodecyloxythioxanthone (14.3 g, 62%) with mp 79–80° C. The identity of this compound was shown by 1H NMR to have the following structure:

1. custom1-Chloro-4-dodecyloxythioxanthone was prepared
2. temperaturerefluxed for 10 min
3. temperatureunder reflux
4. customquenched with water (500 mL)
5. filtrationThe obtained solid was filtered
6. washwashed with water
7. custompurified
8. customby recrystalized from isopropanol