HRID1766651

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID11776

Triphenylphosphine

C18H15P

结构：Cc1cc([N+](=O)[O-])c2c(c1Oc1ccc(OCc3ccccc3)c(CCl)c1)CCC2

HCID23031167

未命名化合物

PRODUCTS

生成物

结构：Cc1cc([N+](=O)[O-])c2c(c1Oc1ccc(OCc3ccccc3)c(C[P+](c3ccccc3)(c3ccccc3)c3ccccc3)c1)CCC2.[Cl-]

HCID21110566

未命名化合物

收率 75.7%

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID1140

Toluene

C7H8

PROCEDURE

实验过程

A suspension of 4-(4-benzyloxy-3-chloromethylphenoxy)-5-methyl-7-nitroindane (2.04 g) and triphenylphosphine (1.39 g) in toluene (50 mL) was heated under reflux for 12 hours. The reaction mixture was allowed to cool to room temperature. Precipitate was collected by filtration, and washed with diethyl ether to give the title compound (2.50 g).

WORKUP

后处理

temperaturewas heated
temperatureunder reflux for 12 hours
filtrationPrecipitate was collected by filtration
washwashed with diethyl ether

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-1b7df68d66524eb98830733f71adbc8f
来源数据集: uspto-grants-2007_06
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07230031B2
来源说明: uspto-grants-2007_06

反应 SMILES

[CH2:1]([O:8][C:9]1[CH:28]=[CH:27][C:12]([O:13][C:14]2[C:22]([CH3:23])=[CH:21][C:20]([N+:24]([O-:26])=[O:25])=[C:19]3[C:15]=2[CH2:16][CH2:17][CH2:18]3)=[CH:11][C:10]=1[CH2:29][Cl:30])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[C:31]1([P:37]([C:44]2[CH:49]=[CH:48][CH:47]=[CH:46][CH:45]=2)[C:38]2[CH:43]=[CH:42][CH:41]=[CH:40][CH:39]=2)[CH:36]=[CH:35][CH:34]=[CH:33][CH:32]=1>C1(C)C=CC=CC=1>[Cl-:30].[CH2:1]([O:8][C:9]1[CH:28]=[CH:27][C:12]([O:13][C:14]2[C:22]([CH3:23])=[CH:21][C:20]([N+:24]([O-:26])=[O:25])=[C:19]3[C:15]=2[CH2:16][CH2:17][CH2:18]3)=[CH:11][C:10]=1[CH2:29][P+:37]([C:38]1[CH:39]=[CH:40][CH:41]=[CH:42][CH:43]=1)([C:44]1[CH:49]=[CH:48][CH:47]=[CH:46][CH:45]=1)[C:31]1[CH:32]=[CH:33][CH:34]=[CH:35][CH:36]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1