Diphenylmethane → Ethyl 3-Hydroxybutyrate
Reaction equation
C([Sn](=[O:10])CCCC)CCC.C1(C[C:18]2[CH:23]=CC=CC=2)C=CC=CC=1.C([C:26](O)([CH2:30][CH3:31])[C:27]([O-:29])=[O:28])C>C(O)C>[CH2:23]([O:29][C:27](=[O:28])[CH2:26][CH:30]([OH:10])[CH3:31])[CH3:18]Participants
5
Reactant 3
Product 1
Reagents, catalysts & solvents 1
Conditions
- Temperature
- 180 °C
Procedure
Ethyl-3-hydroxybutyrate was prepared from a PHA (poly 3-hydroxybutyrate) as follows. A solution of 1.0 g of poly 3-hydroxybutyrate (94% purity) in 4.0 ml of absolute ethanol was prepared in a glass pressure bottle. The PHA was derived from biomass. 10.5 mg of di-butyl tin oxide and 0.5 ml of diphenylmethane were added as a catalyst and as an internal gas chromatographic standard, respectively. The mixture was heated to 180° C. with magnetic stirring. After 2.0 hours the percent yield of ethyl-hydroxybutyrate from the PHA was 77.8%, and after 4.0 hours the percent yield of ethyl-hydroxybutyrate from the PHA was 92%.
Sources & evidence
- ORD record
- ord-2aa95b6e36504b8fa47688df4771f50b
- Source dataset
- uspto-grants-2007_06
- Patent number
- US07230144B2
Reaction notes
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