Cesium carbonate → HCID 23720678, compound

Participants

Reaction Steps

A solution of 2-(4-methyl-1-piperazinyl)acetic acid (described in J. Med. Chem., 43, 1493 (2000); 2.5 g, 16 mmol) in water (30 ml) was cooled to 0° C., and cesium carbonate (2.6 g, 7.9 mmol) was added thereto with stirring, then the mixture was stirred at room temperature for 1 hour. The mixture was concentrated under reduced pressure to give the title compound (4.49 g, 98% yield) as a pale yellow solid.

Provenance & Evidence