Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Nitric Acid | HCID 944 | — |
| Reactant | 2-Methyl-5-Nitroaniline | HCID 7444 | — |
| Reactant | Cyanamide | HCID 9864 | — |
| Solvent | Ethanol | HCID 702 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 178426711 | HCID 178426711 | — |
Reaction Steps
To a suspension of 10.0 g (0.065 mol) of 2-amino-4-nitrotoluene in ethanol (20 ml) was added 65% nitric acid (4.6 ml, 0.065 mol) dropwise at 0° C. and stirred for 10 minutes. Cyanamide (8.32 g, 0.198 mol) in water (5 ml) was added to the reaction mixture then was refluxed for 25 hours, cooled to 0° C. and filtered and washed with water to yield 2-methyl-5-nitrophenyl-guanidine nitrate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07232825B2 |
|---|
| Source dataset | uspto-grants-2007_06 |
|---|
| ORD ID | ord-ffc1bd39709d41449f9b9e31d848dc4c |
|---|
| Source note | uspto-grants-2007_06 |
|---|
