反应详情

A suspension of N-(2-methyl-5-nitrophenyl)-4-(3-pyridyl)-2-pyrimidine-amine (1.5 g, 4.6 mmol) and palladium on active carbon (150 mg, 10%) in ethyl acetate (100 ml) was hydrogenated under a hydrogen atmosphere for 2 hours. The reaction was filtered and the filtrate was concentrated to give N-(5-amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidine-amine for future use without further purification.

1. filtrationThe reaction was filtered
2. concentrationthe filtrate was concentrated