Guanidine Hydrochloride → 1314911-69-7

Temperature

140 °C

To a solution containing 6.7 g (41.6 mmol) of 2-methyl-1,3-propanediamine hydrochloride (Tetrahedron (1994) 50(29), 8617–8632) in 50 ml of methanol was added 83 ml of a solution of sodium methylate in methanol (1 mmol/ml) and the resulting mixture was treated with 3.97 g (41.6 mmol) of guanidine hydrochloride. The reaction mixture was heated at 140° C. for 3 h. The solution was filtered, the solvent evaporated and the residue obtained was used directly in the next step.

1. filtrationThe solution was filtered
2. customthe solvent evaporated
3. customthe residue obtained

ORD record

ord-c4a07bf23a5049b18806558ab5bac8e2

Source dataset

uspto-grants-2007_06

DOI

10.6084/m9.figshare.5104873.v1

Patent number

US07232827B2