Hydrochloric Acid → (4-Benzyloxymethyl-1-phenylcyclohexyl)dimethylamine Hydrochloride

HRID 1767108Notes

Reaction equation

HRID 1767108 reaction equation
[CH2:1]([O:8][CH2:9][CH:10]1[CH2:15][CH2:14][C:13]([N:22]([CH3:24])[CH3:23])([C:16]2[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=2)[CH2:12][CH2:11]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[ClH:25]>>[ClH:25].[CH2:1]([O:8][CH2:9][CH:10]1[CH2:11][CH2:12][C:13]([N:22]([CH3:24])[CH3:23])([C:16]2[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=2)[CH2:14][CH2:15]1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 9928813HCID 9928813, compound

Product 1

HCID 9928812(4-Benzyloxymethyl-1-phenylcyclohexyl)dimethylamine Hydrochloride

Procedure

As described for Example 1, 278 mg of the more polar diastereoisomer of (4-benzyloxymethyl-1-phenylcyclohexyl)dimethylamine were also obtained and this was converted analogously to 305 mg of the corresponding hydrochloride.

Workup

  1. customwere also obtained

Sources & evidence

ORD record
ord-2a7f98bf4a1c4b98949da8b5e7e1dffa
Source dataset
uspto-grants-2007_06
Patent number
US07232847B2

Reaction notes

Loading…