Benzoic acid, 2-amino-5-iodo- → HCID 23030470, compound

HRID 1767155Notes

Reaction equation

HRID 1767155 reaction equation
[I:1][C:2]1[CH:10]=[C:6]([C:7]([OH:9])=[O:8])[C:5]([NH2:11])=[CH:4][CH:3]=1.CO.[NH3:14]>>[I:1][C:2]1[CH:10]=[C:6]([C:7]([O-:9])=[O:8])[C:5]([NH2:11])=[CH:4][CH:3]=1.[NH4+:14]

Participants

3

Reactant 2

HCID 72911Benzoic acid, 2-amino-5-iodo-HCID 21705897Ammonia methanol

Product 1

HCID 23030470HCID 23030470, compoundYield 85%

Procedure

In a 200 mL volume glass vessel equipped with a stirrer and a thermometer were placed 10.0 g (38 mmol) of 5-iodoanthranilic acid and 100 mL (780 mmol) of 15 wt. % ammonia methanol solution. The reaction was carried out for 3 hours at room temperature. After the reaction was complete, the reaction mixture was concentrated under reduced pressure, to obtain 9.0 g (isolated yield: 85%) of ammonium 5-iodoanthranilate as pale red solid.

Workup

  1. customIn a 200 mL volume glass vessel equipped with a stirrer
  2. concentrationthe reaction mixture was concentrated under reduced pressure

Sources & evidence

ORD record
ord-28df87ce9b7a4d42a46530a956db5946
Source dataset
uspto-grants-2007_06
Patent number
US07232903B2

Reaction notes

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