2-(4-Fluorobenzyloxy)-5-trifluoromethylphenylboronic acid → 6-{2-[5-Trifluoromethyl-2-(4-fluorobenzyloxy)phenyl]cyclopent-1-enyl}pyridine-2-carboxylic Acid Methyl Ester

Participants

Role	Name	HCID	Charge
Reactant	2-(4-Fluorobenzyloxy)-5-trifluoromethylphenylboronic acid	HCID 21112921	—
Reactant	6-(2-Bromocyclopent-1-enyl)-pyridine-2-carboxylic acid methyl ester	HCID 69508078	—
Product	6-{2-[5-Trifluoromethyl-2-(4-fluorobenzyloxy)phenyl]cyclopent-1-enyl}pyridine-2-carboxylic Acid Methyl Ester	HCID 69508331	—

Reaction Steps

Prepared by general procedure 3 but using 6-(2-bromocyclopent-1-enyl)-pyridine-2-carboxylic acid methyl ester instead of 3-(2-bromocyclopent-1-enyl) -benzoic acid ethyl ester and 2-(4-fluorobenzyloxy)-5-trifluoromethylphenylboronic acid instead of 5-chloro-2-methoxyphenylboronic acid.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US07232821B2
Source dataset	uspto-grants-2007_06
ORD ID	ord-2dcd5b9aa80c4c649aef9c39897d46a2
Source note	uspto-grants-2007_06