HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(2,4-Difluorobenzyloxy)-5-trifluoromethylphenylboronic acid → 6-{2-[5-Trifluoromethyl-2-(2,4-difluorobenzyloxy)phenyl]cyclopent-1-enyl}-pyridine-2-carboxylic Acid Methyl Ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(2,4-Difluorobenzyloxy)-5-trifluoromethylphenylboronic acid | HCID 21112905 | — |
| Reactant | 6-(2-Bromocyclopent-1-enyl)-pyridine-2-carboxylic acid methyl ester | HCID 69508078 | — |
| Product | 6-{2-[5-Trifluoromethyl-2-(2,4-difluorobenzyloxy)phenyl]cyclopent-1-enyl}-pyridine-2-carboxylic Acid Methyl Ester | HCID 69508200 | — |
Reaction Steps
Prepared by general procedure 3 but using 6-(2-bromocyclopent-1-enyl) -pyridine-2-carboxylic acid methyl ester instead of 3-(2-bromocyclopent-1-enyl)benzoic acid ethyl ester and 2-(2,4-difluorobenzyloxy)-5-trifluoromethylphenylboronic acid instead of 5-chloro-2-methoxyphenylboronic acid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07232821B2 |
| Source dataset | uspto-grants-2007_06 |
| ORD ID | ord-05620beedcfb47d3b7c114734518fa70 |
| Source note | uspto-grants-2007_06 |