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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1767228Generated: November 1, 2026

Acetyl chloride → 3-{2-[5-Trifluoromethyl-2-(4-fluorobenzyloxy)phenyl]cyclopent-1-enyl}-6-acetamidobenzoic Acid Ethyl Ester

https://huagongshe.com/reaction/1767228

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetyl chlorideHCID 6367—
Reactant3-{2-[5-Trifluoromethyl-2-(4-fluorobenzyloxy)phenyl]cyclopent-1-enyl}-6-aminobenzoic Acid Ethyl EsterHCID 69507902—
Product3-{2-[5-Trifluoromethyl-2-(4-fluorobenzyloxy)phenyl]cyclopent-1-enyl}-6-acetamidobenzoic Acid Ethyl EsterHCID 69507658—

Reaction Steps

Prepared by general procedure E but using acetyl chloride instead of propionyl chloride and 3-{2[5-trifluoromethyl-2-(4-fluorobenzyloxy)phenyl]cyclopent-1-enyl}-6-aminobenzoic acid ethyl ester instead of 5-[2-(2-benzyloxy-5-chlorophenyl)-cyclopent-1-enyl]-2-aminobenzoic acid methyl ester.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07232821B2
Source datasetuspto-grants-2007_06
ORD IDord-f61c2374576d433ebe9f7a439cc5968e
Source noteuspto-grants-2007_06