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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1767229Generated: November 1, 2026

Acetyl chloride → 3-{2-[5-Trifluoromethyl-2-(2,4-difluorobenzyloxy)phenyl]cyclopent-1-enyl}-6-acetamidobenzoic acid ethyl ester

https://huagongshe.com/reaction/1767229

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetyl chlorideHCID 6367—
Reactant3-{2-[5-Trifluoromethyl-2-(2,4-difluorobenzyloxy)phenyl]cyclopent-1-enyl)-6-aminobenzoic Acid Ethyl EsterHCID 69507662—
Product3-{2-[5-Trifluoromethyl-2-(2,4-difluorobenzyloxy)phenyl]cyclopent-1-enyl}-6-acetamidobenzoic acid ethyl esterHCID 69507760—

Reaction Steps

Prepared by general procedure E but using acetyl chloride instead of propionyl chloride and (3-{2-[5-trifluoromethyl-2-(2,4-difluorobenzyloxy)phenyl]cyclopent-1-enyl}-6-aminobenzoic acid ethyl ester instead of 5-[2-(2-benzyloxy-5-chlorophenyl)-cyclopent-1-enyl]-2-aminobenzoic acid methyl ester.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07232821B2
Source datasetuspto-grants-2007_06
ORD IDord-d3bfe7e15ab74297a011eba5c3ac82b5
Source noteuspto-grants-2007_06