Isobutyryl chloride → HCID 69508361, compound

HRID 1767236Notes

Reaction equation

[CH3:1][O:2][C:3](=[O:31])[C:4]1[CH:9]=[C:8]([C:10]2[CH2:14][CH2:13][CH2:12][C:11]=2[C:15]2[CH:20]=[C:19]([Cl:21])[CH:18]=[CH:17][C:16]=2[O:22][CH2:23][C:24]2[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=2)[CH:7]=[C:6]([NH2:30])[CH:5]=1.[CH3:32][CH:33]([CH3:37])[C:34](Cl)=[O:35]>>[CH3:1][O:2][C:3](=[O:31])[C:4]1[CH:9]=[C:8]([C:10]2[CH2:14][CH2:13][CH2:12][C:11]=2[C:15]2[CH:20]=[C:19]([Cl:21])[CH:18]=[CH:17][C:16]=2[O:22][CH2:23][C:24]2[CH:25]=[CH:26][CH:27]=[CH:28][CH:29]=2)[CH:7]=[C:6]([NH:30][C:34](=[O:35])[CH:33]([CH3:37])[CH3:32])[CH:5]=1

Participants

Reactant 2

HCID 62325Isobutyryl chloride

HCID 58887633HCID 58887633, compound

Product 1

HCID 69508361HCID 69508361, compound

Procedure

Prepared by general procedure E but using 5-[2-(2-benzyloxy-5-chlorophenyl)-cyclopent-1-enyl]-3-aminobenzoic acid methyl ester instead of 5-[2-(2-benzyloxy-5-chlorophenyl)-cyclopent-1-enyl]-2-aminobenzoic acid methyl ester and 2-methylpropionyl chloride instead of propionyl chloride.

Workup

customPrepared by general procedure E

Sources & evidence

ORD record: ord-9fbce29f31e445959cda30a3c90e8929
Source dataset: uspto-grants-2007_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07232821B2

Reaction notes

Loading…