HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(2,4-Difluorobenzyloxy)-5-trifluoromethylphenylboronic acid → 2{2-[5-Trifluoromethyl-2-(2,4-difluorobenzyloxy)phenyl]cyclopent-1-enyl}-pyridine-4-carboxylic Acid Ethyl Ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(2,4-Difluorobenzyloxy)-5-trifluoromethylphenylboronic acid | HCID 21112905 | — |
| Reactant | 2-(Bromocyclopent-1-enyl)pyridine-4-carboxylic acid ethyl ester | HCID 69508157 | — |
| Product | 2{2-[5-Trifluoromethyl-2-(2,4-difluorobenzyloxy)phenyl]cyclopent-1-enyl}-pyridine-4-carboxylic Acid Ethyl Ester | HCID 69507773 | — |
Reaction Steps
Prepared by general procedure B(iii) but using [5-trifluoromethyl-2-(2,4-diflurobenzyloxy)phenyl]boronic acid instead of (5-chloro-2-benzyloxyphenyl)-boronic acid and 2-(bromocyclopent-1-enyl)pyridine-4-carboxylic acid ethyl ester instead of 3-(2-bromo-cyclopent-1-enyl)-6-methyl benzoic acid ethyl ester
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07232821B2 |
| Source dataset | uspto-grants-2007_06 |
| ORD ID | ord-f9a1902317ee49f084ff90304828dff5 |
| Source note | uspto-grants-2007_06 |