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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1767243Generated: October 30, 2026

2-Benzyloxy-5-trifluoromethylphenylboronic acid → 3-{2-[5-Trifluoromethyl-2-(benzyloxy)phenyl]cyclopent-1-enyl}-5-methylbenzoic Acid Ethyl Ester

https://huagongshe.com/reaction/1767243

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Benzyloxy-5-trifluoromethylphenylboronic acidHCID 23005339—
Reactant3-(2-Bromocyclopent-1-enyl)-5-methylbenzoic acid ethyl esterHCID 69507739—
Product3-{2-[5-Trifluoromethyl-2-(benzyloxy)phenyl]cyclopent-1-enyl}-5-methylbenzoic Acid Ethyl EsterHCID 69508136—

Reaction Steps

Prepared by general procedure B(iii) but using [5-trifluoromethyl-2-(benzyloxy)phenyl]boronic acid instead of (5-chloro-2-benzyloxyphenyl)boronic acid and 3-(2-bromocyclopent-1-enyl)-5-methylbenzoic acid ethyl ester instead of 3-(2-bromocyclopent-1-enyl)-6-methylbenzoic acid ethyl ester.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07232821B2
Source datasetuspto-grants-2007_06
ORD IDord-ab88f722d0f2454f93ad789839a31827
Source noteuspto-grants-2007_06