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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1767244Generated: October 31, 2026

5-Fluoro-2-methoxyphenylboronic acid → 6-{2-[5-Fluoro-2-(methoxy)phenyl]cyclopent-1-enyl}pyridine-2-carboxylic Acid Ethyl Ester

https://huagongshe.com/reaction/1767244

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Fluoro-2-methoxyphenylboronic acidHCID 2782673—
Reactant6-(2-Bromocyclopent-1-enyl)-pyridine-2-carboxylic acid ethyl esterHCID 57862433—
Product6-{2-[5-Fluoro-2-(methoxy)phenyl]cyclopent-1-enyl}pyridine-2-carboxylic Acid Ethyl EsterHCID 69508018—

Reaction Steps

Prepared by general procedure B(iii) but using 5-fluoro-2-methoxyphenylboronic acid instead of (5-chloro-2-benzyloxyphenyl)boronic acid and 6-(2-bromocyclopent-1-enyl)-pyridine-2-carboxylic acid ethyl ester instead of 3-(2-bromocyclopent-1-enyl)-6-methylbenzoic acid ethyl ester.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07232821B2
Source datasetuspto-grants-2007_06
ORD IDord-33dfe235e2244ad184a51aac7c30d752
Source noteuspto-grants-2007_06