反应详情

温度

90 °C

Sulphuric acid (5 drops) was added to 3-bromo-5-fluorobenzoic acid (1.194 g, 5.45 mmol) in ethanol (10 ml) and refluxed with stirring at 90° C. for 17 hours. Reaction mixture partitioned between diethyl ether and water, washed with sodium hydrogen carbonate, dried (MgSO4) and evaporated to dryness.

1. temperaturerefluxed
2. customReaction mixture
3. custompartitioned between diethyl ether and water
4. washwashed with sodium hydrogen carbonate
5. dry with materialdried (MgSO4)
6. customevaporated to dryness