Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | 3-Bromo-5-fluorobenzoic acid | HCID 2773339 | — |
| Catalyst | Sulfuric Acid | HCID 1118 | — |
| Product | Ethyl 3-Bromo-5-fluorobenzoate | HCID 43476807 | — |
Reaction Steps
Sulphuric acid (5 drops) was added to 3-bromo-5-fluorobenzoic acid (1.194 g, 5.45 mmol) in ethanol (10 ml) and refluxed with stirring at 90° C. for 17 hours. Reaction mixture partitioned between diethyl ether and water, washed with sodium hydrogen carbonate, dried (MgSO4) and evaporated to dryness.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07232821B2 |
|---|
| Source dataset | uspto-grants-2007_06 |
|---|
| ORD ID | ord-e896d59eecb94405a6fb45a596741757 |
|---|
| Source note | uspto-grants-2007_06 |
|---|
