4,5-Dichloro-1,2-phenylenediamine → HCID 11749369, compound

HRID 1767598Notes

Reaction equation

HRID 1767598 reaction equation
[Cl:1][C:2]1[C:7]([Cl:8])=[CH:6][C:5]([NH2:9])=[C:4]([NH2:10])[CH:3]=1.C([O:15][C:16](=O)[CH2:17][C:18](=O)[C:19]1[CH:24]=[CH:23][CH:22]=[C:21]([C:25]2[CH:26]=[N:27][CH:28]=[CH:29][CH:30]=2)[CH:20]=1)(C)(C)C>C1(C)C(C)=CC=CC=1>[Cl:1][C:2]1[C:7]([Cl:8])=[CH:6][C:5]2[NH:9][C:16](=[O:15])[CH2:17][C:18]([C:19]3[CH:24]=[CH:23][CH:22]=[C:21]([C:25]4[CH:26]=[N:27][CH:28]=[CH:29][CH:30]=4)[CH:20]=3)=[N:10][C:4]=2[CH:3]=1

Participants

4

Reactant 2

HCID 792974,5-Dichloro-1,2-phenylenediamineHCID 112664733-Oxo-3-(3-pyridin-3-yl-phenyl)-propionic acid tert-butyl ester

Product 1

HCID 11749369HCID 11749369, compound

Reagents, catalysts & solvents 1

HCID 7237O-XyleneSolvent

Procedure

Compound 1 was prepared from 4,5-dichlorophenylenediamine (Compound J18) (172 mg, 0.97 mmol) and 3-oxo-3-(3-pyridin-3-yl-phenyl)-propionic acid tert-butyl ester (K1) (289 mg, 0.97 mmol) by refluxing in xylene according to the general procedure M. Obtained as an off-white solid (310 mg). MS (ISP) 382.2 [(M+H)+], 384 [(M+2+H)+] and 386 [(M+4+H)+]; mp 241° C.

Sources & evidence

ORD record
ord-1e913c74927141b0be21dd7c8ad944b5
Source dataset
uspto-grants-2007_06
Patent number
US07235547B2

Reaction notes

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