Benzaldehyde → 2-Phenyl-2,3-dihydro-benzo[e][1,3]oxazin-4-one

HRID 1767604Notes

Reaction equation

[OH:1][C:2]1[CH:10]=[CH:9][CH:8]=[CH:7][C:3]=1[C:4]([NH2:6])=[O:5].[CH:11](=O)[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1>>[C:12]1([CH:11]2[NH:6][C:4](=[O:5])[C:3]3[CH:7]=[CH:8][CH:9]=[CH:10][C:2]=3[O:1]2)[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1

Participants

Reactant 2

HCID 240Benzaldehyde

HCID 5147Salicylamide

Product 1

HCID 2455042-Phenyl-2,3-dihydro-benzo[e][1,3]oxazin-4-one

Procedure

2-Hydroxybenzamide was transformed by Method G (using benzaldehyde). M.p. 157–160° C.

Sources & evidence

ORD record: ord-c3598c151b024acc83bce59b21b932a9
Source dataset: uspto-grants-2007_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07235548B2

Reaction notes

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