1,2-Dimethoxyethane → 4-[(7-chloro-4-methyl-1H-indol-5-yl)amino]-5-{4-[2-(4-methylpiperazin-1-yl)ethoxy]phenyl}nicotinonitrile
Reaction equation
[CH3:31][N:32]1[CH2:33][CH2:34][NH:35][CH2:36][CH2:37]1.[CH3:38][O:39][CH2:40][CH2:41][O:42][CH3:43].[Cl:1][CH2:2][CH2:3][O:4][c:5]1[cH:6][cH:7][c:8](-[c:11]2[cH:12][n:13][cH:14][c:15]([C:16]#[N:17])[c:18]2[NH:19][c:20]2[c:21]([CH3:30])[c:22]3[cH:23][cH:24][nH:25][c:26]3[c:27]([Cl:29])[cH:28]2)[cH:9][cH:10]1>>[CH2:2]([CH2:3][O:4][c:5]1[cH:6][cH:7][c:8](-[c:11]2[cH:12][n:13][cH:14][c:15]([C:16]#[N:17])[c:18]2[NH:19][c:20]2[c:21]([CH3:30])[c:22]3[cH:23][cH:24][nH:25][c:26]3[c:27]([Cl:29])[cH:28]2)[cH:9][cH:10]1)[N:35]1[CH2:34][CH2:33][N:32]([CH3:31])[CH2:37][CH2:36]1Participants
4
Sources & evidence
- ORD record
- ord-b65d1dce93a24939ab478ff34c16143b
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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