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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1767888Generated: November 3, 2026

Sodium Hydroxide → {6-[2-(4-Trifluoromethyl-phenyl)-thiazol-5-ylmethoxy]-indol-1-yl}-acetic acid

https://huagongshe.com/reaction/1767888

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium HydroxideHCID 14798—
Reactant{6-[2-(4-Trifluoromethyl-phenyl)-thiazol-5-ylmethoxy]-indol-1-yl}-acetic acid tert-butyl esterHCID 69279690—
Product{6-[2-(4-Trifluoromethyl-phenyl)-thiazol-5-ylmethoxy]-indol-1-yl}-acetic acidHCID 11441840—

Reaction Steps

In analogy to the procedure described in example 2 c], {6-[2-(4-trifluoromethyl-phenyl)-thiazol-5-ylmethoxy]-indol-1-yl}-acetic acid tert-butyl ester was treated with NaOH to obtain {6-[2-(4-trifluoromethyl-phenyl)-thiazol-5-ylmethoxy]-indol-1-yl}-acetic acid as orange solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07235572B2
Source datasetuspto-grants-2007_06
ORD IDord-0cfeccc1263440bca4890dc614e913f2
Source noteuspto-grants-2007_06