HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Iodide → HCID 69280203, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Iodide | HCID 4875 | — |
| Reactant | Cesium carbonate | HCID 10796 | — |
| Reactant | 5-(1-Chloroethyl)-4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazole | HCID 23614514 | — |
| Reactant | (5-Hydroxy-indol-1-yl)-acetic acid ethyl ester | HCID 57675474 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 69280203 | HCID 69280203 | — |
Reaction Steps
In analogy to the procedure described in example 1 a], (5-hydroxy-indol-1-yl)-acetic acid ethyl ester was reacted with [rac)-5-(1-chloro-ethyl)-4-methyl-2-(4-trifluoromethyl-phenyl)-thiazole in the presence of cesium carbonate and potassium iodide in N,N-dimethylformamide for 4 h at ambient temperature to give the title compound as yellow solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07235572B2 |
| Source dataset | uspto-grants-2007_06 |
| ORD ID | ord-7b5ec86f9ea7496f8b6cdf283793b555 |
| Source note | uspto-grants-2007_06 |