huagongshe.com
HRID1767939

反应详情

EQUATION

反应方程式

HRID 1767939 的结构方程式

REACTANTS

反应物

2
结构：[Li+].[OH-]
HCID3939

Lithium hydroxide anhydrous

HLiO

结构：Cc1nc(-c2ccc(C(F)(F)F)cc2)sc1CCOc1ccc2c(C)cn(CC(=O)OC(C)(C)C)c2c1
HCID69279704

未命名化合物

PRODUCTS

生成物

1
结构：Cc1nc(-c2ccc(C(F)(F)F)cc2)sc1CCOc1ccc2c(C)cn(CC(=O)O)c2c1
HCID11340466

未命名化合物

PROCEDURE

实验过程

In analogy to the procedure described in example 2 c], (3-methyl-6-{2-[4-methyl-2-(4-trifluoromethyl-phenyl)-thiazol-5-yl]-ethoxy}-indol-1-yl)-acetic acid tert-butyl ester was treated with LiOH to obtain (3-methyl-6-{2-[4-methyl-2-(4-trifluoromethyl-phenyl)-thiazol-5-yl]-ethoxy}-indol-1-yl)-acetic acid as off-white solid.