HuagongsheHuagongshe Chemistry Print Report · For research reference only
Aluminium lithium hydride → {2-[2,3-Difluoro-4-(trifluoromethyl)phenyl]-4-methyl-1,3-thiazol-5-yl}methanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Aluminium lithium hydride | HCID 21226445 | — |
| Reactant | HCID 69280529 | HCID 69280529 | — |
| Product | {2-[2,3-Difluoro-4-(trifluoromethyl)phenyl]-4-methyl-1,3-thiazol-5-yl}methanol | HCID 23614483 | — |
Reaction Steps
In analogy to the procedure described for example 8 c], 2-(2,3-difluoro-4-trifluoromethyl-phenyl)-4-methyl-thiazole-5-carboxylic acid ethyl ester was reduced with lithium aluminum hydride to give [2-(2,3-difluoro-4-trifluoromethyl-phenyl)-4-methyl-thiazol-5-yl]-methanol as white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07235572B2 |
| Source dataset | uspto-grants-2007_06 |
| ORD ID | ord-1d7a0246a94a403c833d9aaccef829f2 |
| Source note | uspto-grants-2007_06 |