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HRID1767987

反应详情

EQUATION

反应方程式

HRID 1767987 的结构方程式

REACTANTS

反应物

3
结构：[H-].[Na+]
HCID24758

Sodium hydride

HNa

结构：CC(C)(C)OC(=O)CBr
HCID79177

Acetic acid, bromo-, 1,1-dimethylethyl ester

C6H11BrO2

结构：Cc1nc(-c2ccc(C(F)(F)F)cc2)sc1COc1ccc2c(C)c[nH]c2c1
HCID23614496

未命名化合物

PRODUCTS

生成物

1
结构：Cc1nc(-c2ccc(C(F)(F)F)cc2)sc1COc1ccc2c(C)cn(CC(=O)OC(C)(C)C)c2c1
HCID69280387

未命名化合物

PROCEDURE

实验过程

In analogy to the procedure described in example 27 f], 3-methyl-6-[4-methyl-2-(4-trifluoromethyl-phenyl)-thiazol-5-ylmethoxy]-1H-indole was reacted with tert-butyl bromoacetate in the presence of sodium hydride to obtain {3-methyl-6-[4-methyl-2-(4-trifluoromethyl-phenyl)-thiazol-5-ylmethoxy]-indol-1-yl}-acetic acid tert-butyl ester as brown oil.