HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diethyl Ether → HCID 23614751, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diethyl Ether | HCID 3283 | — |
| Reactant | 6,6-Dimethyl-5,7-dioxaspiro(2.5)octane-4,8-dione | HCID 79720 | — |
| Reactant | 4-(3-Fluoro-benzyloxy)-phenylamine | HCID 16775314 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 23614751 | HCID 23614751 | 57% |
Reaction Steps
A solution of 561 mg (2.6 mmol) 4-(3-fluoro-benzyloxy)-phenylamine and 448 mg (2.6 mmol) 6,6-dimethyl-5,7-dioxa-spiro[2,5]octane-4,8-dione in 2 ml dichloromethane is refluxed for 16 hours. 5 ml of diethylether is added and the precipitate filtered off to yield 485 mg (57%) of a colorless solid. MS: m/e=330.2 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07235581B2 |
| Source dataset | uspto-grants-2007_06 |
| ORD ID | ord-887ca0e0f2cb43fbbd4fb69c4c39d088 |
| Source note | uspto-grants-2007_06 |